Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) represent one of the most effective infectious disorders. Modern medicines and treatment strategies have turned the widely spreading infection into a manageable condition. In this blog, we explain how HIV medication works, the primary medicine classes, frequently prescribed treatments, and their manufacturer and exporters.
What is HIV, and How Does Treatment Work?
HIV is a virus that attacks the body’s immune system — specifically, the CD4 cells (T cells), which help the immune system fight off infections. Untreated, it slowly erodes the immune system and catapults its victim into full-blown AIDS, the disease’s most advanced stage of infection.
ART remains the mainstay of therapy for HIV. They would include medication combinations that stop the virus multiplying, and support patients to:
How Antiretrovirals Work?
HIV products target the virus at different stages in its life cycle to work effectively. HIV medications help in reducing the level of HIV in a person’s body when taken correctly. This allows the immune system to recover and remain healthy.
ART (antiretroviral therapy) is a class of medicines that includes HIV. Most individuals get three HIV medications from at least two different medication classes.
Functions of HIV Treatments
ART medications disrupt the HIV at crucial points.
- Prevention of HIV from getting into healthy cells and attaching.
- At this point, reverse transcription takes place in the cytoplasm of the resting immune cell, blocking the virus’s ability to convert RNA into DNA.
- On the other hand, blocking HIV DNA from attaching itself to human DNA.
- Then, the formation of new virus particles is prevented by Assembly and release.
Class of Antiretroviral (ARV) medications
Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs):
These medications inhibit reverse transcriptase, an enzyme that H.I.V. requires in order to create DNA from its RNA. NRTIs are frequently used as the foundation of ART combinations.
Common NRTIs include:
- Abacavir
- Emtricitabine
- Lamivudine
- Tenofovir
- Zidovudine
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
NNRTIs, too, inhibit reverse transcriptase but with a twist. They attach directly to the enzyme and prevent it from functioning.
Well-known NNRTIs:
- Efavirenz
- Nevirapine
Efavirenz is one of the old NNRTIs and works well, but it can at times cause sleep and mood changes.
Integrase Strand Transfer Inhibitors (INSTIs)
INSTIs inhibit integrase, the enzyme that puts HIV’s DNA into human DNA. They have become the class of choice for most new HIV regimens because they work so well and are generally well-tolerated.
Examples:
- Dolutegravir
- Bictegravir
- Raltegravir
Protease Inhibitors (PIs)
PIs block protease, an enzyme that makes it possible to create new virus particles. They are usually paired with a “booster” medication such as ritonavir, which enhances their effectiveness.
Examples:
- Darunavir
- Atazanavir
- Lopinavir/ritonavir
Why Adherence Matters
The following are important for good ART adherence:
- Achieving and maintaining viral suppression
- Preventing resistance
- Reducing transmission risk
A World-Leading Company for Antiretroviral Products Manufacturing and Exporting: Sunrise Remedies
Quality-assured and affordable antiretrovirals (ARVs) are essential in the fight against HIV/AIDS and other viral diseases worldwide. Sunrise Remedies Pvt. Ltd., we have become one of the world’s top antiretroviral (ARV) manufacturers and exporters, contributing significantly to better healthcare in developing and developed countries.
Sunrise Remedies, with two decades of experience as a pharmaceutical producer, has proven its reliability to distributors as well as the healthcare exports in many countries around the world.
Why Sunrise Remedies for Antiretroviral Products?
- 30+ years’ experience in the production of pharmaceuticals
- A further reason is world leader in ARV products manufacturing and export
- WHO-GMP & ISO certified facilities
- Broad portfolio of antiretroviral and antiviral products
- Robust international regulatory and export capabilities
- Another reason is quality medicines at affordable prices for the world markets
WHO-GMP Certified Manufacturing Excellence
Not only that, but quality is the basis of Sunrise Remedies success. The brand’s state-of-the-art WHO-GMP approved manufacturing facilities ensure consistent quality products in the most hygienic environment, with an integrated world-class infrastructure and well supported by high-class equipment and technology.
Quality Highlights:
- WHO-GMP compliant manufacturing
- ISO 9001:2015 certified processes
- Advanced quality testing laboratories
- Strict regulatory and pharmacovigilance compliance
This quality commitment is what makes antiretrovirals from Sunrise Remedies comply with global healthcare standards.
Global Exporter of Antiretroviral Medicines
Sunrise Remedies is also leading as an exporter of ARV medicines in many countries in Africa, Asia, etc. It actively helps government tenders, NGOs, hospitals, and international healthcare entities.
Additionally, Major Export Markets Include: Kenya, Nigeria, Ghana, Zambia, Uganda, Tanzania, Ethiopia, Cambodia, Myanmar, Uzbekistan, Congo, and other emerging markets
Through providing affordable and effective ARV items, Sunrise Remedies is also playing a part in the fight against AIDS around the world.
Leadership in Antiretroviral (ARV) Manufacturing
Sunrise Remedies offers the best antiretroviral medicines and is recognized as a top-class manufacturer and exporter of ARV products. The firm manufactures a broad portfolio of both ARV and HIV medicines, which serve as first-line and combination treatments.
- Tenofovir Disoproxil Fumarate (TDF)
- Lamivudine
- Zidovudine
- Efavirenz
- Emtricitabine
- Dolutegravir
- Abacavir
- Nevirapine
- Entecavir (for Hepatitis B)
These ARVs are provided in various dosage forms such as tablets, capsules, and oral solutions, so that flexibility could be accommodated with diverse treatment schedules and requirements of patients.
Worldwide Pharmaceutical Company Specializing in HIV Treatment
So, Sunrise Remedies Pvt. Ltd, Ahmedabad, Gujarat, (India) is a WHO-GMP and an ISO 9001:2015 certified manufacturer of various pharmaceutical products. Started in 1996, developed into a well-known manufacturer and supplier in the worldwide pharmaceutical industry. Sunrise Remedies works with the historic strategies of representatives, which are always associated with such international quality, safety, and efficacy for all our products.
Sunrise Remedies is not only linked with the production of HIV and AIDS products, but also linked with the manufacturing, exporting, and supplying of erectile dysfunction, premature ejaculation, skin care, hair care, cardiac, diabetic, and Ayurvedic products.
Conclusion
Adherence to care is important as HIV infection has become a chronic condition rather than an acute, fatal disease that can now also be managed with antiretroviral therapy (ART). Companies such as Sunrise Remedies play a major role in this war since they offer reliable and effective treatments at an affordable price to anyone, anywhere in the world who is suffering from HIV/AIDS.