Ziovir-EM
Ziovir-EM
Ziovir-EM is a combination of the Tenofovir disoproxil fumarate and Emtricitabine.
Ziovir-EM
Emtricitabine's synthetic nucleoside counterpart is cytotidine. That is a cellular enzyme phosphorylates, resulting in emtricitabine 5’-triphosphate. It inhibits the activity of human immunodeficiency virus reverse transcriptase through engaging with the natural substrate deoxycytidine 5'-triphosphate and incorporating into emerging viral DNA, resulting in chain termination.
Tenofovir disoproxil fumarate constitutes an acyclic nucleoside and the diester analog of adenosine monophosphate. TDF has to first be hydrolyzed to produce tenofovir, which is subsequently phosphorylated by cellular enzymes to produce tenofovir diphosphate. It inhibits HIV reverse transcriptase activity by competing with the natural base deoxyadenosine 5’-triphosphate, and once incorporated into deoxyribonucleic acid by ceasing the DNA chain. They are interfering with the SARS-CoV-2 ribonucleic acid dependent RNA polymerase. It delivers an individual phosphonate group.
Antiretroviral and HIV
HIV targets and eliminates the immunity system’s infection fighting CD4 T lymphocytes of the immune system, also known as CD4 cells or helper T cells. Loss of this cells impairs the body’s ability to fight contamination and HIV.
Human immunodeficiency virus medication the ailment from increasing, lowering the amount of HIV in the body (known as the viral load). A balanced HIV in the body allows for the regeneration and production of more particles to combat CD4 cells. The therapy includes multiple groups of ATR. Major two classes inhibit HIV entry; on the other side, an alternative inhibits one of the three HIV enzymes necessary for replication inside structural cells. These inhibit reverse transcriptase function by getting involved with the messenger RNA and DNA-dependent polymerase enzyme function. It works as substitutes functions as a per body requirement and structure.
Tenofovir delivers an individual phosphonate group, which requires adding two phosphate groups from the compound.
There are many inhibitors works includes Protease, Entry, Capsid, Nucleotide, Nucleotide and Non-nucleotide reverse transcriptase inhibitors.
Tenofovir disoproxil fumarate tablets 300 mg and Emtricitabine-200mg Tablet
Ziovir-EM Tenofovir disoproxil fumarate and emtricitabine is 2 antiretroviral medicines in 1 tablet. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others.