Ziovir contains Tenofovir Disoproxil Fumarate as a main component and belongs to a class of medicine known as endothelin receptor antagonists. It is a bioavailable form of tenofovir, a significant nucleotide analogue reverse-transcriptase constraint with activity against human immunodeficiency ailment and hepatitis B virus.
TDF metabolically converts in the body structure to the present substance. This process is essential for the medicine’s antiviral properties. The gastrointestinal tract absorbs TDF when a healthcare provider administers it. After that, the body processes it into Tenofovir, and cellular enzymes subsequently phosphorylate it to the active form.
ZiovirAn enzyme called a viral reverse transcriptase is the target of tenofovir diphosphate. Both human immunodeficiency viruses and hepatitis B virus utilize transcriptase to convert the RNA genetic material into DNA, which is a crucial phase in their recombination cycle. It is similar to reverse transcriptase’s natural substrates, DNA strand analogs, but with one important distinction.
When the enzyme includes TDF in the viral DNA chain, it causes unnecessary chain termination. Tenofovir may lack the 3'-hydroxyl group required for forming the phosphodiester bonds between nucleotides, which stands DNA synthesis and minimizes the virus from replicating.
The other substantial side of the tenofovir process is affinity and selectivity for viral RNA-dependent human DNA polymerase
As part of an antiretroviral regimen, healthcare providers often combine TDF with other antiretroviral agents to effectively target viral replication. Ingredients work as per body requirement and structure.
A retrovirus is a type of ailment that functions in the opposite direction of human cells. It contains directions that send a signal to produce building blocks for the body structure. This is the nucleotide analog of a substance called 5′-monophosphate and is a dianion at physiological pH and has been linked with the lower membrane permeability and low oral bioavailability.
Sunrise Remedies is the manufacturer of anti-HIV medicine Ziovir Tenofovir Disoproxil Fumarate and other HIV and ARV products.
Tenofovir Disoproxil Fumarate 300mg
It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Tenofovir belongs to a class of drugs known as nucleotide reverse transcriptase inhibitors (NRTIs).