Quinasun
Quinasun
Quinasun is a chloroquine phosphate product, called “antimalaria” and “amebicides” medication. The composition strength is 250 and 500 mg. It generally functions by increasing the level of heme in the red blood, a substance that composed of the malarial parasite. This inhibits the parasite and reduces the infection from spreading in the body.
Quinasun
The characteristics of this composition is thought to numerous activities in antimalarial activity. This is centralize in acidic vacuoles of the leech and function with vital procedure.
In the vital blood cells of the malarial parasite, that is in their lifecycle stage, the acquire amino acid must degrade hemoglobin. It is essential for the parasite's protein and energy metabolism. It is occurring in the vacuole of the parasitic cell.
Hemoglobin cell is production of protein unit and a heme unit. Within this process that infection release the toxic and soluble molecules. The Porphyrin ring known as ferriprotoporphyrin-protoporphyrin-IX makes the hemoglobin moiety. To reduce this molecule toxicity, the Plasmodium vivax bio crystallizes heme needs to transform in hemozoin.
Hemozoin is also known as malaria pigment; a crucial composition of the parasite’s heme detoxification system. That is protecting that from noxious of free hemoglobin released in between this procedure. It gathers in the digestive vacuous as an insoluble particle.
Chloroquine Phosphate Tablets
In addition, chloroquine enters the blood cells by simple diffusion and hinders the Plasmodium vivax cells and the gathering area. This compound becomes protonated after that, as the digestive vacuole acts as an acidic structure; chloroquine cannot leave by spreading.
For the lead bio-crystallization of heme, Chloroquine caps hemozoin molecules. As a result, production of heme in needed cells. After all, it binds with blood to form the chloroquine ferriprotoporphyrin complex; this process is toxic to the cells and disrupts the membrane mechanism. The action of the ferriprotoporphyrin chloroquine results in cell lysis and infective parasite digestion. It does not form hemozoin and is resistant to chloroquine.
chloroquine phosphate 250mg