Meflorise contains Mefloquine 250 mg. This composition serves as an antimalarial for malaria caused by Plasmodium falciparum and vivax, including prophylaxis and chloroquine-resistant strains of P. falciparum.
MefloriseMefloquine includes affinity for the serotonin 5-hydroxytryptamine receptor and, to a minor extent, for the serotonin 5-hydroxytryptamine2C receptor. That acts as an agonist of serotonin. The chiral molecule with asymmetric carbon centers has many different stereoisomers. It targets the 80s ribosome of the plasmodium falciparum, hindering protein synthesis and initiating the subsequent schizonticidal mechanism.
Schizonticide known as schizonts, eliminates the malaria leech within the hemoglobin cells, inhibiting the release of merozoites which cause the cyclical and characteristic symptoms of malaria.
This generic composition is a fluorinated quinoline derivative, which functions as an intraerythrocytic form of the malaria parasite. Its life cycle is multiplex and incorporates at distinct levels.
The bloodstream or cells produce Plasmodium parasites, which develop and multiply inside host erythrocytes. The parasite ingests the cytosol of the infected red cells by a function of endocytosis, during this intra-erythrocytic phase. It may produce reactive oxygen species that may induce membrane and deoxyribonucleic acid damage. The malaria infection commands the heme detoxification system. This transmembrane pathway would function in the parasite to bring substrates necessary for its growth and allow the efflux of toxic chemical structures.
Plasmodium is a species of unicellular eukaryotes that are necessary for the parasites of vertebrates and infection. The procedure cycle of the plasmodium genus includes development in the erythrocyte host, which then enters the parasite into a craniate host during infection.
Meflorise mefloquine belongs to a group of medications called antimalarials. Generally, inhibiting infection, a blood cell infection enters through the bite of an anopheles mosquito. In this process, the infection directly reaches the liver and functions by replicating itself and spreading in the body. It called Merozoites. There, the infection is progressive and developing.
Mefloquine BP 250