Duomal
Duomal
Duomal is Dihydroartemisinin and Piperaquine Phosphate Generic. This is an anti-malarial medication for the malaria pathogen, including Plasmodium falciparum, vivax, and others. Duomal
Through the production of reactive radicals that harm proteins and cellular components and disrupt protein breakdown processes, the composition dihydroartemisinin suppresses malaria parasites. By processing oxidative stress, this system lowers the parasite.
Plasmodium falciparum, which has iron-rich heme groups and lives in red blood cells. The chemical detoxifies heme in the vacuole and interferes with mitochondrial electron transport. Free radicals produced by this mechanism change and breakdown vulnerable proteins.
Piperaquine Phosphate is an antimalarial medication, combined with dihydroartemisinin. Also, that interferes with the detoxification of heme to hemozoin. It is a brown, crystalline pigment produced by the malaria parasite Plasmodium during the digestion of hemoglobin, protecting it from the impact of free heme released during hemoglobin breakdown. It implicated in the development of malaria complications.
Malaria’s parasites occur in the blood in the host’s red blood cubicles, and lead to the release of toxic heme. It also obstructs to parasite’s capability to regenerate and replicate within the host’s bloodstream. Piperaquine phosphate known to hinder the whole process, resulting in a reduction in parasite infection.
Anti-Malarial Products
Antimalarial Medication has been a component in the inhibition against malaria, an ailment caused by plasmodium parasites that enter via the bite of an infected Anopheles mosquito.
Dihydroartemisinin and Piperaquine Phosphate products inhibit the parasite, with less impact on the host body. This function attributed to the vacuoles of the parasite, which is because to its alkalinity. It may control the function of conversion of toxic heme to hemozoin process with the help of inhibiting the biocrystallization of hemozoin. Its action and inhibiting steps are different from each other and work on the body as per the requirements of the body or cells. it may impact the plasma level for inhibiting the infection.
Dihydroartemisinin with Piperaquine Phoshate Tablet